Single-Cell Analysis for Whole-Organism Datasets
نویسندگان
چکیده
منابع مشابه
WholeCellKB: model organism databases for comprehensive whole-cell models
Whole-cell models promise to greatly facilitate the analysis of complex biological behaviors. Whole-cell model development requires comprehensive model organism databases. WholeCellKB (http://wholecellkb.stanford.edu) is an open-source web-based software program for constructing model organism databases. WholeCellKB provides an extensive and fully customizable data model that fully describes in...
متن کاملNon-invasive single-cell biomechanical analysis using live-imaging datasets.
The physiological state of a cell is governed by a multitude of processes and can be described by a combination of mechanical, spatial and temporal properties. Quantifying cell dynamics at multiple scales is essential for comprehensive studies of cellular function, and remains a challenge for traditional end-point assays. We introduce an efficient, non-invasive computational tool that takes tim...
متن کاملWhole organism biocatalysis.
The use of biocatalysts for the industrial synthesis of chemicals has been attracting much attention as an environment-friendly synthetic method. Microbial cells play a leading role in 'chemo-enzymatic synthesis' because of their great diversity. Several microbes with unique catalytic abilities have been found through intensive screening and put to practical use. Besides, advanced molecular bio...
متن کاملCytosplore: Interactive Immune Cell Phenotyping for Large Single-Cell Datasets
Thomas Höllt received the Diplom (MSc) from the University of Koblenz-Landau, Germany, in 2008, and the PhD in computer science from the King Abdullah University of Science and Technology, Saudi Arabia, in 2013. Currently, he is a Postdoctoral fellow at Delft University of Technology working on visualization of high dimensional data, with focus on Cytosplore, a framework for the visual analysis...
متن کاملThe Whole Organism, and nothing but the Organism
Both books draw wonderfully from all levels of evolu-traced to changes in a relatively small number of genes. tion—from considering the developmental differences While all these other considerations are valid, they do between closely related species to macroevolutionary not detract from the clear elegance of the arguments. questions of the origins of phyla. It is in the " deep time " These book...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annual Review of Biomedical Data Science
سال: 2021
ISSN: 2574-3414,2574-3414
DOI: 10.1146/annurev-biodatasci-092820-031008